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Spray drying engineering for extraction of botanical pharmaceutical preparations

Spray drying has been successfully used to encapsulate herbal bioactive compounds, resulting in stable botanicals, a South American medicinal plant with antimalarial, liver protective and antioxidant activity, usually related to its secondary metabolites, flavonoids and polyacetylenes.
2026-05-07 0

Project overview:
  
  Spray drying has been successfully used to encapsulate herbal bioactive compounds, resulting in stable botanicals, a South American medicinal plant with antimalarial, liver protective and antioxidant activity, usually related to its secondary metabolites, flavonoids and polyacetylenes.
  
Engineering operations:
  
  In this work, the physico-chemical stability of the optimized spray-dried composition from aB was evaluated in open containers and sealed sachets under three different stress storage conditions; high performance liquid chromatography was used to monitor the concentrations of the three labeled compounds over a 12-month period, and the color change of stored samples was evaluated using a color spectrophotometer.
  
Engineering tests and results:
  
  In samples stored in open containers, it was observed that the concentrations of monitored plant compounds dropped even more sharply. The degradation rates of the two flavonoids monitored, rutin and hyperin, were lower than those of polyacetylene. The concentration of the marker did not change significantly at ^low temperatures. Regarding color, darker hues were observed at higher temperatures and storage times.
  
  The study showed that storage conditions had a significant impact on the stability of standard spray-dried B.